Wednesday, October 12, 2011

Vitamin C and DNA Damage

Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health

In the study of "The protective role of ascorbic acid on imazalil-induced genetic damage assessed by the cytogenetic tests"by Türkez H, Aydin E., posted in US National Library of Medicine National Institutes of Health, researchers found that AA (Ascorbic acid) alone was not genotoxic and when combined with IMA treatment, reduced the frequencies of CAs and SCEs. A clear dose-dependent decrease in the genotoxic damage of IMA (imazalil) was observed, suggesting a genoprotective role of AA. In conclusion, the preventive role of AA in alleviating IMA-induced DNA damage was indicated for the first time in the present study.

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