Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health
In the study of "Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people" by Malouf R, Grimley Evans J., posted in US National Library of Medicine National Institutes of Health, researchers found that The small number of studies which have been done provide no consistent evidence either way that folic acid, with or without vitamin B12, has a beneficial effect on cognitive function of unselected healthy or cognitively impaired older people. In a preliminary study, folic acid was associated with improvement in the response of people with Alzheimer's disease to cholinesterase inhibitors. In another, long-term use appeared to improve the cognitive function of healthy older people with high homocysteine levels. More studies are needed on this important issue.