Thursday, October 13, 2011

Thiamine (vitamin B1) and Inflammatory Diseases

Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health

In the study of "Protective role of benfotiamine, a fat-soluble vitamin B1 analogue, in lipopolysaccharide-induced cytotoxic signals in murine macrophages" by Yadav UC, Kalariya NM, Srivastava SK, Ramana KV., posted in US National Library of Medicine National Institutes of Health, researchers wrote in abstract that benfotiamine suppresses oxidative stress-induced NF-kappaB activation and prevents bacterial endotoxin-induced inflammation, indicating that vitamin B1 supplementation could be beneficial in the treatment of inflammatory diseases.

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