Friday, December 2, 2011

Vitamin C and Neurotrophic effect

Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health

In the study of "Age-related changes in myosin-V myenteric neurons, CGRP and VIP immunoreactivity in the ileum of rats supplemented with ascorbic acid" by Veit AP, Zanoni JN., posted in US National Library of Medicine National Institutes of Health, researchers found that Ascorbic acid supplementation in the EA345 and EA428 groups increased the average area of myosin-V neurons by 24.6% and 24.1% compared with the E345 and E428 groups, respectively. When all groups were compared, we observed significant differences for the CGRP- and VIP-immunoractive varicosities of nerve fibers from myenteric neurons. Ascorbic acid supplementation had a neurotrophic effect on all neurons studied, suggesting a neuroprotective role.

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