Saturday, December 17, 2011

vitamin C and cellular energy metabolism.

Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health

In the study of "Vitamin C deficiency activates the purine nucleotide cycle in zebrafish" by Kirkwood JS, Lebold KM, Miranda CL, Wright CL, Miller GW, Tanguay RL, Barton CL, Traber MG, Stevens JF., posted in US National Library of Medicine National Institutes of Health, found that irreversibly deaminates AMP to form IMP. We found a 47% increase in AMPD activity in the AA deficient zebrafish, complementary to the 44-fold increase in IMP concentration. These results suggest that vitamin C is crucial for the maintenance of cellular energy metabolism.

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