Monday, December 12, 2011

Life-threatening thiamine deficiency in infants

Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health

In the study of "Outbreak of life-threatening thiamine deficiency in infants in Israel caused by a defective soy-based formula" by Fattal-Valevski A, Kesler A, Sela BA, Nitzan-Kaluski D, Rotstein M, Mesterman R, Toledano-Alhadef H, Stolovitch C, Hoffmann C, Globus O, Eshel G., posted in US National Library of Medicine National Institutes of Health, indicated that Clinician awareness of the possibility of thiamine deficiency even in well-nourished infants is important for early recognition and prevention of irreversible brain damage. Therapy with large doses of thiamine should be initiated at the earliest suspicion of vitamin depletion, even before laboratory evidence is available and before neurologic or cardiologic symptoms appear.

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