Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health
In the study of "Vitamin B1 analog benfotiamine prevents diabetes-induced diastolic dysfunction and heart failure through Akt/Pim-1-mediated survival pathway" by Katare RG, Caporali A, Oikawa A, Meloni M, Emanueli C, Madeddu P., posted in US National Library of Medicine National Institutes of Health, found that vitamin B1 analog benfotiamine (BFT) protects from diabetes mellitus-induced cardiac dysfunction through pleiotropic mechanisms, culminating in the activation of prosurvival signaling pathway. Thus, BFT merits attention for application in clinical practice.
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