Sunday, October 23, 2011

vitamin B12 and folate and From mild cognitive impairment to Alzheimer's disease

Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health

According to the study of "From mild cognitive impairment to Alzheimer's disease - influence of homocysteine, vitamin B12 and folate on cognition over time: results from one-year follow-up" by Siuda J, Gorzkowska A, Patalong-Ogiewa M, Krzystanek E, Czech E, Wiechuła B, Garczorz W, Danch A, Jasińska-Myga B, Opala G., posted in US National Library of Medicine National Institutes of Health, researchers found that Vascular risk factors were found significantly more often in the MCI group (p = 0.041), including APOE4 allele (p = 0.018), hyperhomocysteinaemia (p = 0.012) and folate deficiency (p = 0.023). Discriminant function analysis showed that only age and hypertension are potential factors which may have an influence on progression to dementia in the MCI group within one year of prospective observation.

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