Saturday, November 19, 2011

vitamin B(12) deficiency anemia and Clot formation

Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health

In the study of "White centered retinal hemorrhages in vitamin b(12) deficiency anemia" by Zehetner C, Bechrakis NE., posted in US National Library of Medicine National Institutes of Health, researcher indicated that in megaloblastic anemia, direct anoxia results in endothelial dysfunction. The loss of impermeability allows extrusion of whole blood and subsequent diffusion from the disrupted site throughout and above the nerve fiber layer. Therefore the biomicroscopic pattern of white centered hemorrhages observed in anemic retinopathy is most likely due to the clot formation as the reparative sequence after capillary rupture.

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